You can use cqlsh can to create a secondary index (indexes on column values). This example creates an index on the state and birth_year columns in the users table.
cqlsh:demodb> CREATE INDEX state_key ON users (state);
cqlsh:demodb> CREATE INDEX birth_year_key ON users (birth_year);
Because you created the secondary index on the two columns, the column values can be queried directly:
cqlsh:demodb> SELECT * FROM users
WHERE gender = 'f' AND
state = 'TX' AND
birth_year > 1968
ALLOW FILTERING;