The deployment of Cassandra at Instagram is a challenging problem, especially considering the global placement of our data centers. This talk will cover the motivation and details behind partitioning our data across regional groupings of Cassandra clusters. We integrated with a framework developed internally called Akkio, which allows us to split data into logical units, with strong locality for each unit. We will dive into the details of the placement, access, and migration of data in a geographically partitioned data infrastructure.